We find that the use of sedatives for critically ill patients is still affected by tradition and habits, and it varies from department to department. With the NONSEDA trial we hope to shed light on the possible benefits or harms of being non-sedated. Non-sedation is a complex intervention and has numerous possible consequences, and all of these deserve to be clarified in order to obtain a nuanced picture of whether non-sedation is the way forward. One of these possible consequences is the effect on physical function.