Treatment of chlamydia involves antibiotics. A convenient single-dose therapy for chlamydia is oral azithromycin (Zithromax, Zmax). Alternative treatments are often used, however, because of the high cost of this medication. The most common alternative treatment is doxycycline (Vibramycin, Oracea, Adoxa, Atridox, and others). Unlike gonorrhea, there has been little, if any, resistance of chlamydia to current antibiotics. There are many other antibiotics that also have been effective against chlamydia. As with gonorrhea, a condom or other protective barrier prevents the spread of the infection. Continue Reading