Artisan Spanish cheese is the basic fermented product in
Spanish culture and diet and constitutes a good source of high
quantity and variability of lactic acid bacteria with high proteolytic
capacity. The aim of this study was to isolate high GABA-producing
Lactobacillus strains from a wide variety of artisan Spanish cheeses
and to select those that also showed the highest GABA-production
capacity in wheat flour medium. The importance of this work includes
the possibility of making natural fermentation substrates,
which increase its physiological value. This fermentation offers the
possibility of creating a potentially low-cost functional bakery food
for human consumption. Screening of LAB strains with high GABAproducing
ability could be of interest for food fermented and
pharmaceutical industry in order to obtain probiotic products and
exploit the functional properties of GABA.