There have been attempts to assess the efficacy of garlic (ethanol) extract prepared by simple procedure in lowering blood levels of glucose, triglyceride and cholesterol in comparison with an established product metformin. In the present study, a dose related linear response has been observed with increasing dose of garlic extract in causing hypoglycemia and hypolipidaemia in rabbits. When garlic extract 250 mg/ /kg body weight was administered to normal rabbits, a hypoglycemic and hypolipidaemic response was seen maximally 4 h after the administration of garlic extract when the mean values of