The aim of the treatment of diabetes is to reduce the blood glucose level. Anti-diabetic drug can act in different ways such as stimulation of beta-cell of pancreatic islet to release insulin, to resist the hormones which rise blood glucose, icrease the number and sensitivity of insulin receptors, increase the glycogen content, enhance the use of organ glucose in the tissue, free radicals scavenging, resist lipid peroxidation, correct the metabolic disorder of lipid and protein and promote microcirculation in the body[13].