Uricase is an enzyme participating in the Ænal step
of purine degradation. Uric acid represents the major
catabolite of purine breakdown in humans and for this
reason remains an important marker molecule for
disorders associated with purine metabolism, most
notably gout, hyperuric aemia and the Lesch±Nyhan
syndrome [1]. Methods for rapidly and reliably mon-
itoring urate levels in human Øuids and sera in clinical
diagnoses are desirable