Recent reports suggested that drinking generous
amounts of a mixture of various juices improves the blood lipid profile, reduces oxidative stress, prevents atherogenic
modifications of LDL cholesterol and platelet aggregation
(6–8), and improves HDL-cholesterol concentrations (9). Several
studies have shown that vitamin C plays an important role
in human health, including effects on the immune system (10),
the risk of Alzheimer disease (11), and the efficiency with
which lysosomes in brain glial cells degrade modified proteins
(12). However, no study has examined the bioavailability of
vitamin C in orange juice and its possible beneficial effects on
reducing isoprostane concentrations.