Acne is a common disorder with a high prevalence among adolescents and often it causes atrophic scars [1-3]. The prevalence and severity of acne scars in the population is not well known. Goulden et al. [4] reported an incidence rate of 11% in men and of 14% in women while patients interviewed by Poli et al. [5] believed to have acnes scars in 49% of cases. Layton et al. found that facial scarring affects both sexes equally and occurs quite in 90% of patients with acne. The pathogenesis of atrophic acne scarring is not completely understood, but it is most likely related to inflammatory mediators and enzymatic degradation of collagen fibers. Literature also demonstrated that the incidence of scars is sometimes correlated to the severity of acne but it is strictly correlated also to the delay of starting acne treatment and the duration of inflammatory response [6] Genetic factors, which can determine differences in the process of cell-mediated immune response and in the capacity to respond to tissue damage, are the main factors influencing scar formation [7].