Her Royal Highness Princess Srinagarindra Mahidol was born on Sunday 21 October B.E.2443 [A.D.1900] in Nonthaburi Province. Her given name was Sangvalya. She was the daughter of Phra Janok Choo and Phra Jonani Kham. She was presented to Her Royal Highness Princess Valaya Alongkorn Krom Luang Bejraburi Rajasirindhorn to be at her service. She graduated from the Midwifery and Nursing School at Siriraj Hospital in 1916. In 1917, she was given a scholarship by Her Majesty Somdech Phra Sri Sawarindra Boromarajadevi Phra Phanwasa Ayiga Chao to further her study in nursing in the United States of America, first at the Emerson School in Berkeley, California, where she studied English. The following year she continued her study at North West in Hartford, Connecticut. In 1920, she was married to His Royal Highness Somdech Chao Fah Mahidol Adulyadej Krom Luang Songkla Nagarindra, son of His Majesty King Chulalongkorn and they have three children
Her Royal Highness Princess Galyani Vadhana Krom Luang Naradhiwas Rajanagarindra
His Majesty King Ananda Mahidol
His Majesty King Bhumibol Adulyadej