Other factors may also contribute to the observedchanges in stone disease prevalence. Mean averagetemperature is believed to be a major contributor tovariation in geographic risk for stone disease [15,16]. Datafrom military deployments suggest that the onset oftemperature-related changes in stone risk may occur within90 d [17–20]. For thesereasons, Brikowski and colleagues[21] speculate that temperature-related changes havecontributed to, and may continue to exacerbate, the risingburden of stone disease.