Acinetobacter is emerging as one of the major nosocomial infectious pathogens, facilitated by tolerance
to desiccation and multidrug resistance. Quorum sensing (autoinducer-receptor mechanism) plays role
in biofilm formation in Acinetobacter, though its role in regulation of other virulence factors is yet to be
established. Phylogenetic studies indicate that Acinetobacter baumannii is closely related to Burkholderia
ambifaria but its quorum sensing genes (abaI and abaR) were acquired horizontally from Halothiobacillus
neapolitanus. The prospects of quorum quenching to control the infections caused by Acinetobacter have
also been discussed