Minor cross matching using donor's serum or plasma and recipient’s
cells should not be necessary as tests for complete and incomplete
unexpected antibodies in donor samples are mandatory.
SELECTION OF BLOOD AND COMPONENTS FOR TRANSFUSION
Whole blood, red cell components
Recipient should receive ABO type specific compatible whole blood or
red blood cell components. In the absence of ABO type specific blood,
group O packed red cells should be transfused. Rh(D) negative recipient
should receive Rh(D)negative whole blood or red blood cell components
except for reasonable qualifying circumstances when Rh positive may be
issued only when Rh antibodies are absent and with due consent of
treating physician. Rh(D) positive recipient can receive either Rh(D) positive
or negative whole blood or red blood cell components.
If clinically significant unexpected antibodies are detected in recipient,
whole blood or red blood cells component which do not have
corresponding antigens and are compatible should be transfused. On
reasonable qualifying circumstances indicated by the clinician, a least
incompatible unit should be issued, and the clinician should be instructed
to transfuse under constant observation.