The modeled human CFTR’s NBD1–NBD2 heterodimer by protein–protein
docking (top view). The NBD1 and NBD2 are represented by ribbons and colored in
cyan (NBD1) and green (NBD2), including signature motif (red), Walker A motif
(blue), Walker B motif (magenta), and Q-loop (yellow). The ATP molecules are
shown in stick mode for reference (pink). The figurewas prepared byUCSF Chimera
[37]