Conclusion
Patients diagnosed with hypertension are prescribed large number
of medications for appropriate therapy which increasing the risk
of side effects and drug interactions. But there are several electro
analytical methods reported by Gupta et al. [33-40]. In this article
UV and HPLC methods for the determination of captopril in active
material, pharmaceutical formulations and biological specimens are
reviewed alone or in combination with other drugs. HPLC methods
generally required expensive equipment, provision for use and
disposal of solvents, labor-intensive sample preparation procedure and
personal skilled in chromatographic techniques. In addition, most of
the HPLC methods reviewed have the potential application to clinical
research of drug combination, multi-drug pharmacokinetics studies
and interactions studies. Novelty of this method is these are less time
consuming and very cheap solvents are used.