DISCUSSION
Ulcers are caused due to an imbalance between
mucosal integrity and aggressive factors.
For maintenance of the mucosal integrity, different
therapeutic agents, including plant extracts,
are used to inhibit gastric acid secretion or to
stimulate the mucosal defense mechanism by increasing
the mucosal production of the surface
epithelial cells, or by interfering with mediators
synthesis 9 . The present study was carried out
to evaluate the anti-ulcer activity of ACE against
different animal models of ulcers