A gas chromatography mass spectrometry (GC–MS) method has been developed and fully
validated for the simultaneous determination of natural borneol (NB) and its metabolite, camphor, in rat
plasma. Following a single liquid–liquid extraction, the analytes were separated using an HP-5MS
capillary column (0.25 mm 30 m 0.25 μm) and analyzed by MS in the selected ion monitoring mode