Dermal wound healing, in which transforming growth factor beta 1 (TGFb1) plays an
important role, is a complex process. Previous studies suggest that vitamin D has a potential
regulatory role in TGFb1 induced activation in bone formation, and there is cross-talk
between their signaling pathways, but research on their effects in other types of wound
healing is limited. The authors therefore wanted to explore the role of vitamin D and its
interaction with low concentration of TGFb1 in dermal fibroblast-mediated wound healing
through an in vitro study.