As a consequence of GST π inhibition, vitamin E also significantly attenuated detoxification of BPDE by GST π (149722 BPDE-DNA adducts /107 nucleotides; Po0.05).
The resulting net effect is an increase in BPDE-DNA adducts (Fig. 2B).
As a consequence of GST π inhibition, vitamin E also significantly attenuated detoxification of BPDE by GST π (149722 BPDE-DNA adducts /107 nucleotides; Po0.05).
The resulting net effect is an increase in BPDE-DNA adducts (Fig. 2B).