A one year prospective study covering the year 2001 was conducted in the department of pathology
Goverment medical college Srinagar Kashmir india The bone marrow smears were routinely stain and Perl"s reaction periodic acid schiff and sudam black stain were used as and when required of the 318 bone marrow simples studied during the year 2001 eight cases contain metastatic deposits All of the patients in our present study had pallor (anaemia) as one of the main symptoms and underwent bone marrow aspiration to determine which type of aneamia they were suffering from In patients with metastatic deposites the normal haemopoietic cells of the bone marrow are replaced by tumour cells resulting in my elopathesic anemia and later on they are liabie to develop myeloid metaplasia and myclofibrosis In most of the case the bone marrow was difficult to aspirate especially in cases of epithelial cell deposits with mostly cancerous cells obtained in abackground of peripheral blood a fact that has already been reported