1a archaic :quality of sound :tone
b :manner of utterance :intonation; specifically :phonetic modulation
2a :a pleasing succession of musical tones :melody
b :a dominant theme
3 :correct musical pitch or consonance —used chiefly in the phrases in tune and out of tune
4a archaic :a frame of mind :mood
b :agreement, harmony
c :general attitude :approach
5 :amount, extent