Although a moderate number of respondents indicated that
they used IVIG or probiotics for treatment or prevention of CDI,
neither modality was used consistently, and neither of these agents
is recommended by the SHEA/IDSA guidelines. Compared to these
other non-antibiotic therapies, much more enthusiasm was reported
for FMT, despite a relative lack of experience with the
approach. Eighty percent of respondents would recommend
treatment with FMT for recurrent CDI, and 24% would consider FMT
for treatment of severe disease. The majority of the respondents
reported that FMT should be considered after the second or third
recurrence. Only 9% of respondents would not recommend FMT
under any circumstances.