, the percentage of radical inhibition gave up to 40%, while the best performance was achieved by the alpha-tocopherol/curcumin sample (about 100%).
However, the resveratrol/curcumin samples ensured an optimalperformance in terms of cumulative amount of antioxidants per-meated across the skin, regardless of the best formulation wasthe T60-T-C, which showed the best results in terms of percuta-neous permeation and antiradical activity. For all these reasonsall niosomal formulations showed a potential in the transdermaldelivery of antioxidants molecules and may be useful in cosme-ceutical field for the prevention of diseases caused by oxidativestress.