Diabetic patients were
also more likely to be hypertensive (73.2 vs. 43.9%; p b 0.001) with
greater use of statins (42.0 vs. 15.2%; p b 0.001) and ACE-I/ARBs (51.9
vs. 28.8%; p b 0.001). However, there was no difference in the prevalence
of advanced fibrosis among the DM patients taking or not taking
statins (p= 0.182) and also among the DM patients taking or not taking
ACE-I/ARB (p = 0.357). There were differences in ALT, albumin,
platelet count, TG, LDL and HbA1C between the two groups. There was
no difference in aggregated length of liver tissue examined between patients
with and without DM (19.9 mm vs. 18.2 mm; p = 0.225). As
shown in Table 2, patientswith diabetes hadmore lobular inflammation
(p= 0.017), ballooning (p b 0.001) and NASH (p b 0.001). Themedian
NAS was higher in DM patients compared to non-DM patients (p =
0.022). More of the DM patients had grade 2 ballooning (41.7% vs.
24.0%; p b 0.001) and higher prevalence of NASH (80.2% vs. 64.4%;
p b 0.001) compared to non-DM patients, while there was no differences
in steatosis between patients with and without DM. DM patients
also had a higher prevalence of advanced fibrosis (40.3% vs. 17.0%;
p b 0.001) [Table 1]