The absolute difference in body
weight between the orlistat and placebo
groups was 2.2 kg (i.e., a total of a
9.4-kg weight loss in the orlistat group
versus a 7.2-kg weight loss in the placebo
group after 3 years’ follow-up). Treatment
success, as defined as losing at least 5% of
initial body weight, was achieved by 67%
in the orlistat group compared with 56%
in the placebo group after 3 years. The
waist circumference was reduced 2–3 cm
more in the orlistat group compared with