MATERIALs AND METHODS
This was a case control study conducted in the Department of
Biochemistry in collaboration with the Department of Obstetrics
and Gynaecology at Gauhati Medical College & Hospital, Guwahati
(Assam) between July, 2012 to July, 2013. The study included 50
primigravida women already diagnosed with pre-eclampsia in third
trimester of pregnancy. They comprised the case group. Fifty age
and gestational age matched healthy normotensive primigravida
women with normal pregnancy were included in the control group.
All the study subjects were in the age group 18-25 years and from
diverse socio- economic status. A thorough history and physical
examination was done and women with twin/multiple pregnancy,
history of hypertension, diabetes mellitus, autoimmune disorders,
renal, hepatic or thyroid gland diseases, intake of drugs which affect
lipid metabolism, smoking and alcohol abuse were excluded from
the study.