We do not know much about possible
synergistic or additive effects of flavonoids and the nutrient
antioxidants, such as vitamins C or E. The view that flavonoids are
irrelevant to human health and/or disease may need to be modified in
view of the potentially health-promoting activities of the flavonoids
that have recently been reported in experimental (Middleton and
Kandaswami, 1993) and epidemiological studies (Hertog et al., 1993a,