Histamine toxicity from fish makes up 5% of food-borne disease outbreaks reported to the CDC, but is likely highly underreported. During 1998-2008, 262 confirmed and 71 suspected outbreaks of histamine fish poisoning were reported to the CDC. Taken together, these affected 1,383 people, causing a total of 59 hospitalizations. In the great majority of cases, the fish that caused the outbreak was prepared in a restaurant or deli