The aim of this work was to study the extraction behavior of the main coffee antioxidants (caffeoylquinic
acids, melanoidins and caffeine) and the antioxidant capacity, during brewing time in the most widely consumed
coffee brew methods (filter and espresso) in coffee. Antioxidant capacity by colorimetric assays
(Folin–Ciocalteau, ABTS and DPPH) and electron spin resonance spectroscopy techniques (Fremy's salt and
TEMPO) were analyzed. In espresso coffee, more than 70% of the antioxidants (except dicaffeoylquinic
acids, diCQA) of a coffee brew were extracted during the first 8 s. In filter coffee, a U-shape antioxidants extraction
profile was observed, starting later (after 75 s) in Vietnam coffee than in Guatemala one, probably
due to different wettability. Other technological parameters, such as turbulences and a longer contact time
between water and ground coffee in filter coffeemaker, increased extraction efficiency, mainly in less polar
antioxidant compounds as diCQA. In conclusion, these technological factors should be considered to optimize
coffee antioxidants extraction that can be used as ingredients for functional foods.