The UF with a flow rate of 650 mL min−1,the time required for the concentration of viruses ranged from 3.30 to 17.10 h using the smaller cartridge could be completed in 2.10–2.50 h using the larger cartridge. The time to obtain the viral concentrate through various steps of coarse filtration, MF and UF using the smaller TFF cartridges required about 7.40–38.30 h, and this time was considerably reduced to less than 7.2 h using the TFF cartridges with larger surface areas (Table 3).