. In the present study, a dose related linear response has been observed with increasing dose of garlic extract in causing hypoglycemia and hypolipidaemia in rabbits. When garlic extract 250 mg/ /kg body weight was administered to normal rabbits, a hypoglycemic and hypolipidaemic response was seen maximally 4 h after the administration of garlic extract when the mean values of glucose, triglyceride and cholesterol decreased significantly (p < 0.05)