Tango gives Axe health regeneration in the laning stage, allowing him to survive against most forms of enemy harass.
Stout Shield is crucial on a melee hero like Axe, as the damage block drastically increases his survivability against attacks, whether they be from enemy heroes or neutral creeps.
Ring of Protection gives Axe additional armor, further increasing his survivability against physical damage. It also allows Axe to build Tranquil Boots from the Side Lane Shop, boosting his efficiency.
Iron Branch is a cheap item that allows Axe to shore up his attributes with his remaining gold. It can be sold for inventory space as needed, or built into a Magic Wand.