This research aimed to develop the information system for infant and children of preschool age growth monitoring. The system was able to run with 2 platform, which were Android Operating System and Web Application, in order to support different kind of users. The objectives of the system were not only for reducing time spend and error on recording and assessing of growth and development, but also improving the performance and efficiency of such processes. The Android application was developed for the parents, who had to record the growth and development of their children. On the other hand, the Web application was developed for those healthcare staffs to ease the monitoring of the records from those parents. After evaluated by 5 experts and 30 users, the result of satisfaction level was an average of 4.61 with 0.39 standard deviation. The result could be concluded that the satisfaction rate on the developed system was in a very good level and reach the objectives of the research. Therefore, the deployment of the monitoring system will help improving the performance and quality of growth monitoring process efficiently.