This antibiotic resistance was usually
intrinsic character. Although LAB strains are species dependent
intrinsic resistance to
sulfamethoxazole-trimethoprim [13], all LAB strainsin our study showed intrinsic resistance to
sulfamethoxazole-trimethoprim which they may have
some antagonistic components such as
p-aminobenzoic acid and thymidine [14]. All LAB
strains in this study showed intrinsic resistance to
vancomycin, these strains were due to the presence of
D-alanine ligase and this enzyme could be inactivated
vancomycin activity [15]. Acquired antibiotic
resistances in some LAB strains in this study showed
resistant to penicillin, ampicillin and tetracycline.