cally applied Polygonum multiflorum extract (4.7 mg/12cm2) on the
shaved dorsal skin of telogenic C57BL/6 mice for 1, 2, 3, and 4weeks.
Each weak we evaluated the degree of hair growth by observing the
skin color. At 2 week, we observed Polygonum multiflorum extract
induced black coloration in the shaved skin of telogenic C57BL/6
mice, while neither less visible hair growth nor black coloration
was observed in control group (Fig. 1). At 4 week, we observed that
hair growth from control group was confined to the proximal parts
of epidermis, emphasizing its dormancy, while Polygonum multiflorum
extract treated group showed overall hair growth which was
not confined to the proximal parts (Fig. 1).