massive hemorrhage or hemorrhage in a vital organ were considered as the cause of death if this was the patient’s terminal event. Extensive infarction was considered the cause of death if it occurred in a vital organ such as the brain, the heart, or the lungs. Organ failure was defined as severe impairment in the function of a vital organ, which was in- compatible with life, as a consequence of drug toxicity or a disease process other than those specified above. Carcinomatosis was defined as causing death in those patients having a severe metabolic or nutritional abnormality which precipitated death, in addition to wide- spread malignancy without any of the other causes already mentioned.