Thirty-two grain-fed veal calves (177 ± 6.7 kg body weight (BW)) were used in a completely randomized block design experiment to determine effects of feeding corn diets naturally contaminated with Fusarium mycotoxins and/or a modified yeast cell wall extract (YCW) on performance, immunity and carcass characteristics. Calves were fed one of four dietary treatments in individual pens for at least 84 days either: (1) control corn + supplemental pellet (CC), (2) control corn + YCW supplemental pellet (CY), (3) mycotoxin contaminated corn + supplemental pellet (MC), and (4) mycotoxin contaminated corn + YCW supplemental pellet (MY). Diets consisted of 750 g/kg whole corn grain and 250 g/kg supplemental pellet with corn as the source of food-borne mycotoxins. The major contaminants present in the contaminated diets (average concentrations of MC and MY) were deoxynivalenol (DON; 10.27 mg/kg), 15-acetyl DON (1.27 mg/kg) and zearalenone (1.84 mg/kg). Final BW and total BW gain of the calves were not different between treatment groups. However, ADG tended (P=0.07) to be higher and F:G was decreased (P=0.003) in calves fed contaminated diets. Haptoglobin, fibrinogen and IgA concentrations did not differ between treatments. Concentrations of IgG were lower (P=0.003) in calves receiving YCW. Plasma urea N and glucose concentrations were increased (P