Seafood forms a part of a healthy diet. However, seafood can be contaminated with foodborne pathogens,
resulting in disease outbreaks. Because people consume large amounts of seafood, such disease outbreaks
are increasing worldwide. Seafood contamination is largely due to the naturally occurring phenomenon
of biofilm formation. The common seafood bacterial pathogens that form biofilms are Vibrio
spp., Aeromonas hydrophila, Salmonella spp., and Listeria monocytogenes. As these organisms pose a
global health threat, recent research has focused on elucidating methods to eliminate these biofilmforming
bacteria from seafood, thereby improving food hygiene. Therefore, we highlight recent advances
in our understanding of the underlying molecular mechanisms of biofilm formation, the factors
that regulate biofilm development and the role of quorum sensing and biofilm formation in the virulence
of foodborne pathogens. Currently, several novel methods have been successfully developed for controlling
biofilms present in seafood. In this review, we also discuss the epidemiology of seafood-related
diseases and the novel methods that could be used for future control of biofilm formation in seafood.