Margo A. Halm and Rochelle Armola study about Effect of Oral Care on Bacterial Colonization and Ventilator-Associated Pneumonia.They said that Toothbrushing was used less often in patients receiving mechanical ventilation. Interestingly, the strongest evidence for decreasing dental plaque colonization is through mechanical interventions like toothbrushing, but such interventions may be used less frequently in ICUs.