Relatively, few data have been published on the management of pericardial effusion and there is a lack of contemporary prospect- ive series with unselected patients with pericardial effusions of dif- ferent entity (small vs. moderate vs. large). Ongoing prospective studies, registries, and new updated guidelines from medical soci- eties will provide more evidence based data to guide the manage- ment of pericardial effusion. A simplified algorithm for the triage and management of pericardial effusion is illustrated in Figure