D. fragilis is probably transmitted by fecal-oral routeThe Number 2 and transmission via helminth eggs (e.g., Ascaris, Enterobius spp.) has been postulatedThe Number 3. Trophozoites of D. fragilis have characteristically one or two nuclei (The Number 1, The Number 4), and it is found in children complaining of intestinal (e.g., intermittent diarrhea, abdominal pain) and other symptoms (e.g., nausea, anorexia, fatigue, malaise, poor weight gain).