This study examined the role that organizational culture plays in the process of innovation adoption within specialized schools of business, which focus on the professional education of mid-career adults. Faculty (n = 451) at these schools were surveyed about their perceptions of program culture as well as their perceptions and adoption of nine Internet-based innovations used in their teaching and of four Internet-based course-content topics. The conceptual model guiding this study synthesized Rogers' (1995) diffusion of innovations model with the Cameron & Ettington (1988) organizational culture model (based on the Competing Values Framework). The ability to predict adoption using this model was tested through linear regression.