CONCLUSION
From the whole exercise, it may be concluded that the
crude ethanol extract of plant H. integrifolia Planch was
found to possess significant analgesic activity, while ethyl
acetate extracts showed moderate activity, n-butanol and
aqueous extract of the plant showed mild analgesic effects
which indicates its use in the traditional system of
medicine in order to support to reduce pain but further
studies are required to evaluate the mechanism of action
and activity directed bioassay for the new source of drug
development.