A specific service must approve the use of the drug before dispensing. This strategy can be used when inappropriate use or severe adverse effects may occur, and it can also be employed for antimicrobial agents when inappropriate use or overuse can result in resistant organisms and pose a danger to the general patient population or the public. Limiting use of the drug to specially trained individuals. This strategy may be appropriate when the drug is inherently dangerous and should only be used by individuals with specific training (e.g., restricting use of chemotherapy agents to oncologists). Designating medications for use in specific areas. Such policies can be helpful when administration of a medication requires special equipment or staff with particular skills to use the medication safely (e.g., limiting neuromuscular blockers to operating rooms and critical care areas).