Toxic Epidermal Necrolysis (TEN) which is characterized by the detachment of the epidermis from the dermis is a rare
(1.89/1.000.000 annually) and potentially life-threatening condition. The overall mortality is 20 - 30%. TEN is characterized
by sudden apoptosis of keratinocytes leading to mucous membrane erosions and epidermal detachment; detachment of
less than 10% of the total body surface area defines Stevens-Johnson Syndrome (SJS); when greater than 30%, it defines
TEN, while intermediate cases are called SJS/TEN overlap. Many drugs, including prednisolone, cyclosporin, and
intravenous immunoglobulin (IVIG), have been used in an attempt to halt the disease process. The use of phenytoin as a
prophylactic anticonvulsant after brain surgery, particularly for brain tumors, is a common practice, regardless of whether
the patient has a previous history of convulsions. This report described a case of haemorrhagic stroke where phenytoin
use induced TEN.