• Psychopathology
- Especially major depressive disorder, bipolar disorder, conduct disorder, and substance use disorders
- Psychiatric co-morbidity, especially the combination of mood, disruptive, and substance use disorders
- Dysfunctional personality traits (especially antisocial, borderline, histrionic, and narcissistic traits)
- Feelings of hopelessness and worthlessness
- Impulsive aggression: the tendency to react to frustration or provocation with hostility or aggression