Pulsed isfrared ligit therapy alsoalkedanodyme, foo erapy, has not been studied in oncology delivering infrared light in an effort to improve foot be perfusion by stimulating nitric oxide produgion. by a machine, which patients can rent or purchase. Only three ski studies were found that used PILT in diabetic patients with cap neuropathy of those studies, only one cap nical trial design. Leonard, spe and conducted rooqi, and Myers study of2 people with diabetic peripheralshap symptoms, and pain were found for most participants, with the the exception of those with the most severe neuropathy scores one Pul effective too anodyne therapy treatment that improved sensory impairments as measured function and current perception thresholds in delivered over two weeks, the pants after 10 each lasting 40 minutes (Prendergast, Miranda, & Sanchez, CH 2004). Amall et al. G2006 studied 22 subjects with diabetic pai peripheral neuropathy. PILT treatments were given for 30 min in utes threr imes a week over an eightweek period. Si ass Semmes-Weinstein improvements in sensation as measured by monofilaments were found. The Bnding heid cven for those ag with longstanding, profound diabetic peripheral neuropathy. Although no study of PILT demonstrated risks associated with fo the treatment, the small sample sizes, lack of oncologic study er populations, and nonrandomized study designs used in two of & the three studies fail to provide adequate evidence to recom- p mend the use of anodyne therapy in CIPN. Tra uscurta coess aerve stimmulation: Transcutaneous nerve stimulation CTENS) and high-frequency external muscle 906 December 2007