Elevated WC is a clear marker of increased cardiometabolic risk and may add to the assessment of a patient’s risk profile in the clinical setting. Therapeutic lifestyle changes can reduce both visceral adiposity and insulin resistance and
may positively affect all aspects of the metabolic syndrome and reduce cardiometabolic risk. Lifestyle change and metformin therapy have both been shown to halt progression from insulin resistance to T2DM, and other drugs are under investigation for the potential to reduce the risk of progression along the spectrum of obesity to insulin resistance, metabolic syndrome, and T2DM. Bariatric surgical therapies have been successful in achieving remission in T2DM patients. With rising obesity and T2DM rates worldwide, in both adults and children, early intervention in the progression of obesity to other cormorbidities is crucial. In addition, the potentially reinforcing relationship between visceral fat and insulin resistance emphasizes the need to control or reduce weight in patients already diagnosed with T2DM.
Elevated WC is a clear marker of increased cardiometabolic risk and may add to the assessment of a patient’s risk profile in the clinical setting. Therapeutic lifestyle changes can reduce both visceral adiposity and insulin resistance and
may positively affect all aspects of the metabolic syndrome and reduce cardiometabolic risk. Lifestyle change and metformin therapy have both been shown to halt progression from insulin resistance to T2DM, and other drugs are under investigation for the potential to reduce the risk of progression along the spectrum of obesity to insulin resistance, metabolic syndrome, and T2DM. Bariatric surgical therapies have been successful in achieving remission in T2DM patients. With rising obesity and T2DM rates worldwide, in both adults and children, early intervention in the progression of obesity to other cormorbidities is crucial. In addition, the potentially reinforcing relationship between visceral fat and insulin resistance emphasizes the need to control or reduce weight in patients already diagnosed with T2DM.
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