Thin-layer
chromatographic autobiography against these bacteria was
also performed for each extract, while the -mangostin content
was analyzed using a validated HPLC method. Results:
The dichloromethane extract exhibited the strongest antibacterial
effect with minimum inhibitory concentration values
for both bacterial species at 3.91 g/ml, while the minimum
bactericidal concentration values against P. acnes
and S. epidermidis were 3.91 and 15.63 g/ml, respectively.
Thin-layer chromatographic autobiography indicated that
-mangostin was present in all extracts, except the water
extract, and is a major active component against both