In his treatise on Indonchinese nemacheilids, Kottelat (1990) recorded only one species of Schistura from the Mae Khlong basin in southwestern Thailand and referred to it as Schistura desmotes. Recent collections from the basin have included Schistura mahnerti, which is widely distributed in the basin, Schistura balteata, apparently restricted in Thailand to the Pakkok River of the Mae Nam Kwai Noi system, and two recently discovered and described species, Schistura aurantiaca, also widely distributed in the basin, and Schistura tenebrosa, found only in a small region drained by the Pakkok River of the Mae Nam Kwai Noi system (Plongsesthee et al. 2011; Kangrang et al. 2012). A sixth species, discovered in 2011, is described herein. Re-examination of specimens examined by Kottelat (1990) and of many more recently collected specimens indicate that the species in the Mae Khlong previously referred to as S. desmotes is Schistura sexcauda.