A phytochemical investigation reported that oleuropein
was isolated from the leaves of Olea europaea [5]. This
compound is known for possessing a wide range of
pharmacologic and health promoting properties including
anti-arrhythmic, spasmolytic, immuno-stimulant, cardioprotective,
hypotensive, antihyperglycemic, antimicrobial,
and anti-inflammatory effects [6–8]. Olea europaea is also
rich in other bioactive phenolic compounds that are reported
to have anti-inflammatory activities [9] However, there is no
sufficient scientific studies reporting the anti-inflammatory
and analgesic activities of Olea europaea leaves.
As a contribution to the study of the pharmacological
activities of the different components of olive leaves, we
searched the possible anti-inflammatory and antinociceptive
effects of the chloroformic and methanolic olive leaves extracts
using an in vivo experimental models, that is, the
carrageenan-induced hindpaw edema for the anti-inflammatory
activity and the acetic acid-induced abdominal writhing
test for the analgesic activity.